Cancer immunotherapy: how low-level ionizing radiation can play a key role

Radiation Hormesis in Humans Exposed to Low Level Ionizing Radiation

Through various researches and investigations it has been established that high doses of ionizing radiation are harmful to health. There is substantial controversy regarding the effects of low doses of ionizing radiation despite the large amount of work carried out (both laboratory and epidemiological). According to the linear no-threshold (LNT) hypothesis, any amount, however small, of radiati...

Cancer prognosis: can anesthesia play a role?

501 September 2013 S URGERY remains a primary treatment for cancer. It is therefore important to know whether any perioperative factors, including anesthetic(s), can positively or negatively affect the prognosis of cancer. In this issue of AnEsthEsIoloGY, Benzonana et al.1 have reported the effects of anesthetic isoflurane on the growth and migration (malignant potential) of renal cancer cells....

Immunoengineering: How Nanotechnology Can Enhance Cancer Immunotherapy

Although cancer immunotherapy can lead to durable outcomes, the percentage of patients who respond to this disruptive approach remains modest to date. Encouragingly, nanotechnology can enhance the efficacy of immunostimulatory small molecules and biologics by altering their co-localization, biodistribution, and release kinetics.

Risk of low-level ionizing radiation from medical imaging procedures.

Medical imaging procedures with x-ray, computed tomography (CT) and nuclear isotopes use ionizing radiation.1–4 On the other hand, ultrasound and magnetic resonance imaging (MRI) do not. When biological tissues are exposed to radiation, the effects are related to the type of radiation and the amount absorbed. Units of absorbed dose are grays (Gy) (joules/kilogram). One rad (radiation absorbed d...

Late and Low-level Effects of Ionizing Radiation